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 Formulary Chapter 10: Musculoskeletal and joint diseases - Full Chapter
10.01  Expand sub section  Drugs used in rheumatic diseases and gout
10.01  Expand sub section  Rheumatoid arthritis and other inflammatory disorders
10.01  Expand sub section  Osteoarthritis and soft-tissue disorders
Hylan G-F 20 (Synvisc)
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Formulary  
   
10.01.01  Expand sub section  Non-steroidal anti-inflammatory drugs
Celecoxib (Celebrex)
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Formulary Capsules 
   
Diclofenac
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Formulary e/c tablets, soluble tablets, suppositories

m/r tablets once daily, mr/ tablets twice daily

Injection 75 mg/3ml  
Link  NPC: Diclofenac and CV risk review ( 2010)
   
Diclofenac with Misoprostol (Arthrotec 50 and 75)
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Formulary Tablets 
   
Etodolac (Lodine SR)
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Formulary Capsules, m/r tablets 
   
Etoricoxib (Arcoxia)
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Formulary Tablets 
   
Ibuprofen
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Formulary Tablets, m/r tablets, suspension 
Link  UKMI QA: Can breastfeeding mothers take ibuprofen?
   
Indometacin
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Formulary Capsules, m/r capsules 
   
Ketoprofen (Oruvail MR)
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Formulary m/r capsules 
   
Mefenamic Acid
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Formulary Capsules 250 mg, tablets 500 mg 
   
Meloxicam
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Formulary Tablets 
   
Nabumetone
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Formulary Tablets 
   
Naproxen
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Formulary e/c tablets, suspension 
   
Piroxicam
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Formulary Capsules, tablets Feldene Melt 
   
Sulindac
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Formulary Tablets 
   
10.01.01  Expand sub section  Aspirin to top
10.01.02  Expand sub section  Corticosteroids
10.01.02.01  Expand sub section  Systemic corticosteroids
10.01.02.02  Expand sub section  Local corticosteroids injections
Dexamethasone
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Formulary Injection 3.3mg/mL 
   
Dexamethasone Phosphate
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Formulary  
   
Hydrocortisone acetate (Hydrocortistab)
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Formulary Injection 
   
Methylprednisolone Acetate (Depo-Medrone)
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Formulary Injection 
   
Methylprednisolone Acetate (Depo-Medrone with Lidocaine)
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Formulary Injection 
   
Prednisolone Acetate (Deltastab)
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Formulary Injection 
   
Triamcinolone Acetonide (Adcortyl)
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Formulary Injection 
   
Triamcinolone Acetonide (Kenalog)
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Formulary Injection 
   
10.01.03  Expand sub section  Drugs which suppress the rheumatic disease process
10.01.03  Expand sub section  Gold to top
Soldium Aurothomalate (Myocrisin)
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Formulary Injection 
   
10.01.03  Expand sub section  Penicillamine
Penicillamine
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Formulary
Amber
Tablets 
   
10.01.03  Expand sub section  Antimalarials
Hydroxychloroquine (Plaquenil)
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Formulary Tablets 
   
10.01.03  Expand sub section  Drugs affecting the immune response
Abatacept (Orencia)
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Formulary
Red
i/v infusion 
   
Adalimumab (Humira)
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Formulary
Red
Prefilled pen 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
   
Cytotoxic Drug Azathioprine
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Formulary
Amber
Tablets 
   
Baricitinib (Olumiant)
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Formulary
Red
 
Link  NICE TA466 Baricitinib for moderate to severe rheumatoid arthritis (2017)
   
Certolizumab Pegol (Cimzia)
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Formulary
Red
Prefilled syringes 
Link  NICE TA186: Rheumatoid arthritis - certolizumab pegol
   
Ciclosporin
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Formulary Capsules Neoral 
   
Cytotoxic Drug Cyclophosphamide
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Formulary Tablets, injection 
   
Etanercept (Enbrel)
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Formulary
Red
Prefilled syringes 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis - etanercept, infliximab and adalimumab
Link  NICE TA35: Arthritis (juvenile idiopathic) - etanercept
   
Golimumab (Simponi)
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Formulary
Red
Prefilled pen 
Link  NICE TA220: Psoriatic arthritis - golimumab
Link  NICE TA225: Rheumatoid arthritis - golimumab
Link  NICE TA233: Ankylosing spondylitis - golimumab
   
Infliximab (Remicade)
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Formulary
Red
Powder for i/v infusion 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis - etanercept, infliximab and adalimumab
   
Leflunomide
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Formulary Tablets 
Link  MHRA advice regarding risk of hepatotoxicity, haemotoxicity, infections, and birth defects
   
Cytotoxic Drug Methotrexate
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Formulary Tablets 2.5mg only, injection

Prefilled syringe Metoject 
Link  UKMI QA: Methotrexate and alcohol guidance
   
Rituximab (rheumatology) (MabThera)
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Formulary
Red
Concentrate for i/v infusion 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
   
Sarilumab (Kevzara)
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Formulary
Red
 
Link  NICE TA485 Sarilumab for moderate to severe rheumatoid arthritis (2017)
   
Tocilizumab (RoActemra)
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Formulary
Red
Concentrate for i/v infusion 
Link  NICE TA198: Rheumatoid arthritis - tocilizumab
   
Tofacitinib (Xeljanz)
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Formulary
Red
 
Link  NICE TA480 Tofacitinib for moderate to severe rheumatoid arthritis (2017)
   
10.01.03  Expand sub section  Sulfasalazine
Sulfasalazine
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Formulary Tablets, e/c tablets 
   
10.01.04  Expand sub section  Gout and cytotoxic-induced hyperuricaemia to top
10.01.04  Expand sub section  Acute attacks of gout
Colchicine
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Formulary Tablets 
   
10.01.04  Expand sub section  Long-term control of gout
Allopurinol
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Formulary Tablets 
   
Febuxostat (Adenuric )
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Formulary
Amber
Tablets  
Link  MHRA advice regarding risk of serious hypersensitivity reactions
Link  NICE TA164: Hyperuricaemia - febuxostat
   
Probenecid
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Formulary Tablets 
   
10.01.04  Expand sub section  Hyperuricaemia associated with cytotoxic drugs
Rasburicase (Fastertec)
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Formulary i/v innfusion 
   
10.01.05  Expand sub section  Other drugs for rheumatic diseases
10.02  Expand sub section  Drugs used in neuromuscular disorders to top
10.02.01  Expand sub section  Drugs which enhance neuromuscular transmission
10.02.01  Expand sub section  Anticholinesterases
Edrophonium Chloride
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Formulary Injection 
   
Neostigmine
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Formulary
Amber
Injection 
Link  UKMI QA: Converting between Pyridostigmine & Neostigmine
   
Pyridostigmine Bromide (Mestinon)
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Formulary Tablets 
Link  UKMI QA: Converting between Pyridostigmine & Neostigmine
   
10.02.01  Expand sub section  Immunosuppressant therapy
10.02.01  Expand sub section  Acetylcholine-release enhancers
10.02.02  Expand sub section  Skeletal muscle relaxants to top
Baclofen
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Formulary Tablets, oral solution 
Link  EMSCG Commissioning policy for Intrathecal Baclofen (ITB)
   
Dantrolene Sodium
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Formulary Capsules 
   
Diazepam
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Formulary Tablets, oral solution, injections (solution, emulsion), rectal tubes 
   
Tizanidine
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Formulary
Amber
Tablets 
   
10.02.02  Expand sub section  Other muscle relaxants
10.02.02  Expand sub section  Nocturnal leg cramps
Quinine
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Formulary Quinine sulphate tablets 
Link  Cochrane review of the evidence
   
10.03  Expand sub section  Drugs for the treatment of soft-tissue disorders and topical pain relief
10.03  Expand sub section  Extravasation
10.03.01  Expand sub section  Enzymes to top
Hyaluronidase (Hyalase)
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Formulary Injection 
   
10.03.02  Expand sub section  Rubefacients, topical NSAIDs, capsaicin, and poultices
10.03.02  Expand sub section  Topical NSAIDs and counter-irritants
Benzydamine Hydrochloride
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Formulary Cream 
   
Transvasin
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Formulary  
   
Voltarol Emulgel
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Formulary Gel 
   
10.03.02  Expand sub section  Capsaicin
Axsain
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Formulary Cream 0.075% 
   
Capsaicin (Qutenza)
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Restricted Drug Restricted Patches 
   
Capsaicin (Zacin)
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Formulary Cream 0.025% 
   
10.03.02  Expand sub section  Poultices
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

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