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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
08.01.05  Expand sub section  Other antineoplastic drugs
Cytotoxic Drug Carfilzomib (Kyprolis)
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Restricted Drug Restricted
Red

Solution for infusion

 
Link  NICE TA457 Carfilzomib for previously treated multiple myeloma (2017)
   
Cytotoxic Drug Crizotinib (Xalkori)
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Restricted Drug Restricted
Red

Capsule

 
Link  NICE TA406 Crizotinib for untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer (2016)
   
Cytotoxic Drug Ibrutinib  (Imbruvica)
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Restricted Drug Restricted
Red

Capsule

 
Link  NICE TA491 Ibrutinib for treating Waldenstrom’s macroglobulinaemia (2017)
   
Cytotoxic Drug Palbociclib (Ibrance)
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Restricted Drug Restricted
Red

Capsule

 
Link  NICE TA495 Palbociclib with an aromatase inhibitor for previously untreated, hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer (2017)
   
Cytotoxic Drug Ponatinib (Iclusig)
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Restricted Drug Restricted
Red

Tablet

 
Link  NICE TA451 Ponatinib for treating chronic myeloid leukaemia and acute lymphoblastic leukaemia (2018)
   
Cytotoxic Drug Ribociclib (Kiskali)
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Restricted Drug Restricted
Red

Tablet

 
Link  NICE TA496 Ribociclib with an aromatase inhibitor for previously untreated, hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer (2017)
   
Cytotoxic Drug Ruxolitinib (Jakavi®)
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Restricted Drug Restricted
Red

Tablets

 
   
Cytotoxic Drug Venetoclax (Venclyxto)
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Restricted Drug Restricted
Red

Tablet

 
Link  NICE TA487 Venetoclax for treating chronic lymphocytic leukaemia (2017)
   
Acalabrutinib
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Unlicensed Drug Unlicensed
Red

Capsules

 
   
08.01.05  Expand sub section  Amsacrine
08.01.05  Expand sub section  Arsenic trioxide
08.01.05  Expand sub section  Bevacizumab
Bevacizumab (Avastin®)
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Formulary
Amber

Injection

 
Link  MHRA advice: Risk of osteonecrosis of the jaw ( 2011)
Link  NICE TA214: Breast Cancer with taxane
Link  NICE TA263: Breast cancer with capecitabine
   
08.01.05  Expand sub section  Bexarotene to top
Bexarotene (Targretin®)
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Restricted Drug Restricted
Red

Capsule

 
   
08.01.05  Expand sub section  Bortezomib
Bortezomib (Velcade®)
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Formulary
Red
Injection 
Link  NICE TA129: Multiple myeloma - bortezomib
Link  NICE TA228: Bortezomib and thalidomide for the first-line treatment of multiple myeloma
   
08.01.05  Expand sub section  Brentuximab vedotin
08.01.05  Expand sub section  Cetuximab
08.01.05  Expand sub section  Crisantaspase
08.01.05  Expand sub section  Dacarbazine and Temozolomide to top
Cytotoxic Drug Dacarbazine
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Formulary
Red
Injection 
   
08.01.05  Expand sub section  Erlotinib
Cytotoxic Drug Erlotinib (Tarceva® )
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Formulary
Red

Tablets

 
Link  EMCN: Erlotinib regimen in lung cancer
   
08.01.05  Expand sub section  Hydroxycarbamide
Cytotoxic Drug Hydroxycarbamide
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Formulary
Red
Capsules 
   
08.01.05  Expand sub section  Imatinab
08.01.05  Expand sub section  Ipilimumab
08.01.05  Expand sub section  Mitotane to top
08.01.05  Expand sub section  Panitumumab
08.01.05  Expand sub section  Pentostatin
08.01.05  Expand sub section  Platinum compounds
Cytotoxic Drug Carboplatin
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Formulary
Red
Injection 
   
Cytotoxic Drug Cisplatin
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Formulary
Red
Injection 
   
Cytotoxic Drug Oxaliplatin
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Formulary
Red
Injection 
   
08.01.05  Expand sub section  Porfimer sodium and temoporfin
08.01.05  Expand sub section  Procarbazine to top
Cytotoxic Drug Procarbazine
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Formulary
Red
 
   
08.01.05  Expand sub section  Protein kinase inhibitors
Dasatinib (Sprycel®)
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Formulary
Red
Tablets 
   
Erlotinib (Tarceva®)
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Formulary
Red
Tablets 
   
Cytotoxic Drug Imatinib (Gilvec®)
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Formulary
Red
Tablets 
   
08.01.05  Expand sub section  Taxanes
Cytotoxic Drug Docetaxel (Taxotere®)
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Formulary
Red
Concentrate for infusion 
   
Cytotoxic Drug Paclitaxel
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Formulary Concentrate for infusion 
   
08.01.05  Expand sub section  Topoisomerase I inhibitors
08.01.05  Expand sub section  Trabectedin
08.01.05  Expand sub section  Trastuzumab to top
Cytotoxic Drug Trastuzumab (Herceptin®)
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Formulary
Red
Injection 
   
08.01.05  Expand sub section  Tretinoin
Tretinoin (Vesanoid®)
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Formulary
Red
Capsules 
   
 ....
 Non Formulary Items
Crisantaspase  (Erwinase®)

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Non Formulary
 
Gefitinib  (Iressa®)

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Non Formulary
 
Cytotoxic Drug  Irinotecan Hydrochloride  (Campto®)

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Non Formulary
 
Paclitaxel  (Abraxane®)

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Non Formulary
 
Paclitaxel  (Taxol®)

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Non Formulary
 
Sorafenib  (Nexavar®)

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Non Formulary
 
Sunitinib  (Sutent®)

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Non Formulary
 
Temoporfin  (Foscan®)

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Non Formulary
 
Cytotoxic Drug  Topotecan  (Hycamtin®)

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Non Formulary
Link  NICE TA91: Topotecan for ovarian cancer
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Medicines that should be initiated or recommended by a specialist for continuation in primary care  

Green

Medicines suitable for routine use within primary and secondary care  

Red

Medicines which should normally be prescribed by specialists only  

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